Table 2 Functional pathways and categories included in the top enriched pathway in Fig. 1e
Categories | Diseases or functions annotation | P value | Molecules | # Molecules |
|---|---|---|---|---|
Cell-to-cell signaling and interaction, cellular movement, hematological system development and function, immune cell trafficking, inflammatory response | Recruitment of macrophages | 0.0000252 | CD8A, ICAM1, NOTCH1, RHOB | 4 |
Cell-to-cell signaling and interaction | Adhesion of breast cancer cell lines | 0.000206 | CTNND1, ICAM1, SACM1L | 3 |
Cell-to-cell signaling and interaction, cellular movement, hematological system development and function, immune cell trafficking, inflammatory response | Adhesion of macrophages | 0.00091 | ICAM1, RHOB | 2 |
Cancer, cell-to-cell signaling and interaction, organismal injury and abnormalities | Adhesion of myelomonocytic cells | 0.00124 | ICAM1 | 1 |
Cancer, cell-to-cell signaling and interaction, organismal injury and abnormalities | Activation of tumor cells | 0.0013 | CTNND1, NOTCH1 | 2 |
Cell-to-cell signaling and interaction | Adhesion of connective tissue cells | 0.00191 | ATP6AP1, ICAM1, RHOB | 3 |
Cancer, cell-to-cell signaling and interaction, organismal injury and abnormalities | Activation of mammary tumor cells | 0.00248 | CTNND1 | 1 |
Cell-mediated immune response, cell-to-cell signaling and interaction, cellular movement, hematological system development and function, immune cell trafficking | Adhesion of regulatory T lymphocytes | 0.00248 | ICAM1 | 1 |
Cell-to-cell signaling and interaction, cellular assembly and organization, hematological system development and function, hypersensitivity response, immune cell trafficking | Cell–cell adhesion of eosinophils | 0.00248 | ICAM1 | 1 |
Cancer, cell-to-cell signaling and interaction, organismal injury and abnormalities | Activation of leukemic blasts | 0.00248 | NOTCH1 | 1 |