Fig. 7

Effects of QCN on neurotrophins and Akt signaling pathway in the spinal cord of the BPA rats at week 8 post-avulsion. A The protein levels of BDNF and NGF as determined by western blot. Quantification of B BDNF and C NGF protein in the ventral horn of the C6–7 spinal segments. D The protein levels of p-Akt, Bcl-2, Bcl-xL, Bax, Caspase-9, and Caspase-3 as determined by western blot. Quantification of E p-Akt/Akt, F Bcl-2, G Bcl-xL, H Bax, I cleaved caspase-9, and J cleaved caspase-3 proteins in the ventral horn of the C6–7 spinal segments. Data are expressed as the mean ± SEM (n = 3). ^### p < 0.001 vs the sham group; *p < 0.05, **p < 0.01, and ***p < 0.001 vs the vehicle group