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Fig. 4 | Inflammation and Regeneration

Fig. 4

From: A human induced pluripotent stem cell model from a patient with hereditary cerebral small vessel disease carrying a heterozygous R302Q mutation in HTRA1

Fig. 4

Gene expression profiling of SM9-1 iPSCs. a RT-qPCR analysis to examine the expression levels of HTRA1 and associated genes in SM9-1 T lymphocytes and SM9-1 iPSCs compared with healthy iPSCs (201B7, WD39, and 414C2). Values represent the mean ± SEM of technical triplicates; **p < 0.01. b RT-qPCR analysis to compare the expression levels of wild-type and mutant HTRA1 RNA in SM9-1 iPSCs and healthy iPSCs (201B7). Values represent the mean ± SEM of technical triplicates; ***p < 0.001. c, d RT-qPCR analysis to examine the expression levels of NOG and NOTCH3 in SM9-1 T lymphocytes and SM9-1 iPSCs compared with healthy iPSCs (201B7, WD39, and 414C2). Values represent the mean ± SEM of technical triplicates; ***p < 0.001

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Inflammation and Regeneration

ISSN: 1880-8190

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