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Fig. 3 | Inflammation and Regeneration

Fig. 3

From: Regeneration of invariant natural killer T (iNKT) cells: application of iPSC technology for iNKT cell-targeted tumor immunotherapy

Fig. 3

In vivo adjuvant activity of iPSC-iNKT cells in mice. a Adjuvant activity on NK cells induced by iPSC-iNKT cells upon stimulation using αGalCer/DCs. b In vivo tumor cytotoxicity via the adjuvant effect of iPSC-iNKT cells in an ovalbumin (OVA)-dependent manner. EL4 is a B6-derived thymoma line and EG7 is the OVA-expressing EL4 subline. TOG is the administration of OVA-loaded dying spleen cells from TAP–/– mice with αGalCer. Figures are adapted with permission from Watarai et al., J Clin Invest, 2010 [35], Copyright (2010) American Society for Clinical Investigation

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