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Table 1 Clinicopathological characteristics of PM/DM patients

From: Circulating plasma microRNA profiling in patients with polymyositis/dermatomyositis before and after treatment: miRNA may be associated with polymyositis/dermatomyositis

 

Clinical manifestations

Muscle strength (MMT)

Muscle enzymes

 
 

Patients

Age (years)

Sex

Cutaneous involvement

Pulmonary involvement

Upper limbs

Lower limbs

CK (IU/L)

ALD (IU/L)

LDH (IU/L)

Therapy

PM

P01

52

F

–

IP

4

4

1038

20.8

472

PSL 30 mg/day

CyA 150 mg/day

P02

83

F

–

–

4

4

8359

90.4

1224

PSL 40 mg/day

TAC 2 mg/day

P03

45

F

–

IP

4

4

417

21.2

404

PSL 40 mg/day

TAC 3 mg/day

IVCY 500 mg/4 weeks

P04

17

F

–

–

4

4

2737

37.4

448

PSL 50 mg/day

TAC 3 mg/day

P05

46

M

–

–

5

5

2451

17.6

497

PSL 40 mg/day

TAC 3 mg/day

IVCY 500 mg/4 weeks

DM

D01

32

F

H, G, E

IP

4

3

6213

147

569

PSL 50 mg/day

CyA 150 mg/day

D02

18

F

E

–

4

4

17,662

59.1

1349

PSL 50 mg/day

TAC 3 mg/day

D03

62

M

H, G, E

–

4

4

7026

54

955

PSL 80 mg/day

TAC 3 mg/day

D04

40

F

G, E

IP

4

4

4246

106.7

703

PSL 50 mg/day

TAC 3 mg/day

D05

65

M

H, G, E

–

5

5

1176

18.5

410

PSL 60 mg/day

IVCY 500 mg/4 weeks

  1. PM polymyositis, DM dermatomyositis, H heliotrope rash, G Gottron’s sign, E erythema of elbows and/or knees, IP interstitial pneumonia, MMT manual muscle test, CK creatine kinase, ALD aldolase, LDH lactic dehydrogenase, PSL prednisolone, CyA cyclosporine, TAC tacrolims, IVCY intravenous cyclosphosphamide