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Fig. 2 | Inflammation and Regeneration

Fig. 2

From: Age-related dysfunction of the DNA damage response in intestinal stem cells

Fig. 2

Expression of inflammatory factors is decreased in old ISCs. Immunohistochemical analyses of inflammatory factors were performed in young and old jejunum with (IR) or without 10 Gy X-ray irradiation (non-IR). Representative images stained with anti-pNF-κB and anti-IL-6 antibodies, together with graphs of the percentages of positive cells, are shown in a and b, respectively. Arrows and arrowheads indicate GFP and pNF-κB or IL-6 double-positive and GFP single-positive cells, respectively. Data are mean ± s.e.m. (n = 3 and > 100 GFP+ cells). *p < 0.05, **p < 0.01. Scale bars, 50 μm

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