Table 1 The IL-1 family members
IL-1 family members | Receptor | Property |
|---|---|---|
IL-1α | IL-1RI | Inflammatory |
IL-1β | IL-1RI | Inflammatory |
IL-1Ra | IL-1RI | IL-1RI antagonist |
IL-18 | IL-18Rα | Inflammatory |
IL-33 | ST2 | Th2 inflammation |
IL-36Ra | IL-1Rrp2 | IL-1Rrp2 antagonist |
IL-36α | IL-1Rrp2 | Inflammatory |
IL-36β | IL-1Rrp2 | Inflammatory |
IL-36γ | IL-1Rrp2 | Inflammatory |
IL-37 | IL-18Rα | Anti-inflammatory |
IL-38 | IL-1Rrp2 | IL-1Rrp2 antagonist |