Fig. 1
From: Polyrotaxanes as emerging biomaterials for tissue engineering applications: a brief review
One of the schematic of synthesis of the PRX supramolecular assembly. The long axle polymers (blue) are threaded into the ring-shaped molecules (orange) to form the pseudo PRX molecules. Then, end cap molecules (purple) are added to prevent the dethreading of ring molecules, thereby resulting in PRXs. This PRX can be further modified at various sites (green, red, cyan) to impart desirable functionalities according to the application