Fig. 3From: Differentiation, functions, and roles of T follicular regulatory cells in autoimmune diseasesImportance of IL-2 in Tfh/Tfr cell balance. The imbalance of Tfh/Tfr cells leads to defective IL-2 production. Exogenous IL-2 restores the balance between Tfh and Tfr cells, thus offering therapeutic approachesBack to article page