Fig. 1
From: Neurological pathogenesis of SARS-CoV-2 (COVID-19): from virological features to clinical symptoms
Schematic diagram of the coronavirus structure and genomic structure. a The coronavirus genome is single-stranded RNA, which together with nucleocapsid (N) protein constitutes the nucleocapsid. There is an envelope that encloses the nucleocapsid, which consists of spike (S) protein, integral membrane (M) protein, and envelope (E) protein. b ORF1a and ORF1b continue to exist from the 5' end to approximately 20 kbp. Since the pseudoknot structure exists between the two, two patterns of translation products of the 1a region or 1a + 1b region are generated. Other ORFs encode S protein, E protein, M protein, N protein, etc