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Fig. 1 | Inflammation and Regeneration

Fig. 1

From: Interleukin-6: evolving role in the management of neuropathic pain in neuroimmunological disorders

Fig. 1

IL-6 signaling. D1–D3, subdomains of IL-6Rα; gp130, glycoprotein 130; IL-6, interleukin-6; IL-6R, interleukin-6 receptor; JAK, Janus kinase; mAb, monoclonal antibody; MAPK, mitogen-activated protein kinase; sgp, soluble glycoprotein 130; SHP2, Src homology region 2 domain–containing phosphatase-2; sIL-6R, soluble IL-6R; STAT3, signal transducer and activator of transcription 3

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