Fig. 2
From: Interleukin-6: evolving role in the management of neuropathic pain in neuroimmunological disorders
A Role of IL-6 in the pathophysiology of multiple sclerosis. BBB, bloodābrain barrier; CNS, central nervous system; IL, interleukin; ROS, reactive oxygen species; TGF-Ī², transforming growth factor beta; Th, T-helper. B Role of IL-6 in the pathophysiology of NMOSD. AQP4, aquaporin-4; BBB, bloodābrain barrier; CNS, central nervous system; IgG, immunoglobulin G; IL-6, interleukin 6; NMOSD, neuromyelitis optica spectrum disorder; Th, T helper; Treg, regulatory T cell