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Fig. 1 | Inflammation and Regeneration

Fig. 1

From: The roles and mechanisms of senescence-associated secretory phenotype (SASP): can it be controlled by senolysis?

Fig. 1

The effect of SASP factors. SASP factors can re-enforce cellular senescence in a autocrine manner. SASP factors can also act in a paracrine manner, inducing senescence of surrounding cells (paracrine senescence). SASP factors facilitate tissue repair and recruitment of immune cells. SASP factors are involved in development (developmental senescence). On the other hand, SASP factors are associated with chronic inflammation and cancer progression when persist

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Inflammation and Regeneration

ISSN: 1880-8190

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