Fig. 4
From: State-of-the-art liver disease research using liver-on-a-chip
Study of non-alcoholic fatty liver disease/non-alcoholic steatohepatitis using liver-on-a-chip. A A schematic image of the progression of NAFLD/NASH. Created with Biorender.com. B, C To recapitulate liver steatosis observed in patients with NAFLD, a liver-on-a-chip (B) and liver lobule chip (C) were developed. Reprinted with permission from ref [38]. Copyright 2020 John Wiley and Sons. Reprinted with permission from ref [39]. Copyright 2021 Elsevier. D To recapitulate liver fibrosis observed in patients with NASH, a liver-on-a-chip was developed. Reprinted with permission from ref [40]. Copyright 2020 John Wiley and Sons