Fig. 4.

Hypoxic CM from younger NSPCs effectively enhance neurosphere formation. A Neurosphere assay of enriched E11.5 NSPCs under the normoxic or hypoxic CM prepared from enriched E11.5 or E14.5 NSPCs. (mean ± SEM, n = 3, ^a p = 0.00537, ^b p = 0.00983, ^c p = 0.00653). B Neurosphere assay of enriched E14.5 NSPCs under the normoxic or hypoxic CM prepared from enriched E11.5 or E14.5 NSPCs. (mean ± SEM, n = 3, ^a p = 0.0246, ^b p = 0.0262, ^c p = 0.0847).