Fig. 5.

VEGF-A suppresses NSPC apoptosis while promotes NSPC growth. A Detection of apoptotic (upper panels) and proliferated (lower panels) NSPCs derived from E14.5 cortex in the absence or the presence of 10 ng/ml of VEGF-A under the normoxic condition. Scale bar = 100 μm. B Quantification of apoptotic NSPCs (mean ± SEM, n = 4, * p = 0.028). Each black dot indicates the ratio of apoptotic NSPCs in each sample. C Quantification of proliferated NSPCs (mean ± SEM, n = 3, * p = 0.049). Each black dot indicates the ratio of BrdU incorporated NSPCs in each sample.