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Fig. 2 | Inflammation and Regeneration

Fig. 2

From: IFN-γ-STAT1-mediated CD8+ T-cell-neural stem cell cross talk controls astrogliogenesis after spinal cord injury

Fig. 2

Infiltration of CD8+ T cells hindered the locomotor functional recovery of SCI. A BMS score showing locomotor function in Rag2−/− mice with adoptive CD8+ T-cell therapy after SCI. n = 8 independent mice. ****P < 0.0001, ####P < 0.0001, two-way ANOVA-RM with Bonferroni. B BMS scores showing locomotor function in wild-type mice with the administration of anti-CD8 antibody after SCI. n = 8 independent mice. *P < 0.05, **P < 0.01, #P < 0.05, two-way ANOVA-RM with Bonferroni. C Rotarod assays showing ameliorative locomotor functional recovery after administration of anti-CD8 antibody at 35 dpi. n = 8 independent mice. **P < 0.01, Student’s T-test

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Inflammation and Regeneration

ISSN: 1880-8190

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