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Fig. 3 | Inflammation and Regeneration

Fig. 3

From: Injury-induced interleukin-1 alpha promotes Lgr5 hair follicle stem cells de novo regeneration and proliferation via regulating regenerative microenvironment in mice

Fig. 3

Immune cells phenotype in wound healing. A At day 7, 3W mice have less M1 and more M2 protein biomarkers. B At day 3, 3W mice have more M1 and less M2 mRNA levels (n = 6–8). C At day 7, 3W mice have more M1 and M2 mRNA levels (n = 6–8). D At day 10, 3W mice have less M1 and more M2 mRNA levels (n = 6–8). E At third day (D3) and seventh day (D7), there is no difference in macrophage infiltration between 3 and 7W mice. (3W-3D, 40.00 ± 1.864; 7W-3D, 43.00 ± 4.106; 3W-7D, 38.78 ± 1.511; 7W-7D, 38.61 ± 2.170; n = 4.) F Foxp3 and Ctla4 mRNA levels at 3D, 7D, and 10D, respectively. (n = 3) G 3W mice have higher Tgfb1 mRNA expression levels (n = 3). *P < 0.05

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Inflammation and Regeneration

ISSN: 1880-8190

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