Fig. 3From: Facilitation of colonic T cell immune responses is associated with an exacerbation of dextran sodium sulfate–induced colitis in mice lacking microsomal prostaglandin E synthase-1Analysis of splenomegaly and anemia in mPGES-1−/− mice. A Spleen was isolated, imaged and weighed on day 7 after the start of exposure to 1% DSS. B Also on day 7, morphological analysis of the spleen was performed by H&E staining. Representative images are shown. Scale bar, 500 μm. C Erythrocyte count, hemoglobin (HGB) concentration, and hematocrit (HCT) in the peripheral blood were measured on day 7 after the start exposure to 1% DSS. *P < 0.05; 2-way ANOVA followed by Tukey multiple comparison test (n = 3 to 17)Back to article page