Skip to main content

Articles

Page 1 of 6

  1. Aging of the global population increases the incidence of osteoporosis and associated fragility fractures, significantly impacting patient quality of life and healthcare costs. The acute inflammatory reaction ...

    Authors: Junichi Kushioka, Simon Kwoon-Ho Chow, Masakazu Toya, Masanori Tsubosaka, Huaishuang Shen, Qi Gao, Xueping Li, Ning Zhang and Stuart B. Goodman
    Citation: Inflammation and Regeneration 2023 43:29
    Content type: Review Published on:

  3. Invariant natural killer T (iNKT) cells are a subset of innate-like T cells restricted by a major histocompatibility complex (MHC) class I-like molecule, CD1d. iNKT cells express an invariant T cell receptor (...

    Authors: Takahiro Aoki, Shinichiro Motohashi and Haruhiko Koseki
    Citation: Inflammation and Regeneration 2023 43:27
    Content type: Review Published on:

  5. Authors: Cassandra Margotta, Paola Fabbrizio, Marco Ceccanti, Chiara Cambieri, Gabriele Rufolo, Jessica D’Agostino, Maria Chiara Trolese, Pierangelo Cifelli, Veronica Alfano, Christian Laurini, Silvia Scaricamazza, Alberto Ferri, Gianni Sorarù, Eleonora Palma, Maurizio Inghilleri, Caterina Bendotti…
    Citation: Inflammation and Regeneration 2023 43:25
    Content type: Correction Published on:

    The original article was published in Inflammation and Regeneration 2023 43:19

  6. Human mesenchymal stromal cell (MSC)-derived extracellular vesicles (EV) revealed neuroprotective potentials in various brain injury models, including neonatal encephalopathy caused by hypoxia–ischemia (HI). H...

    Authors: Nicole Labusek, Yanis Mouloud, Christian Köster, Eva Diesterbeck, Tobias Tertel, Constanze Wiek, Helmut Hanenberg, Peter A. Horn, Ursula Felderhoff-Müser, Ivo Bendix, Bernd Giebel and Josephine Herz
    Citation: Inflammation and Regeneration 2023 43:24
    Content type: Research article Published on:

  7. Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL) is an inherited cerebral small vessel disease (CSVD) caused by biallelic mutations in the high-temperature req...

    Authors: Emi Qian, Masahiro Uemura, Hiroya Kobayashi, Shiho Nakamura, Fumiko Ozawa, Sho Yoshimatsu, Mitsuru Ishikawa, Osamu Onodera, Satoru Morimoto and Hideyuki Okano
    Citation: Inflammation and Regeneration 2023 43:23
    Content type: Rapid communication Published on:

  8. Despite progress in developing wound care strategies, there is currently no treatment that promotes the self-tissue repair capabilities. H2 has been shown to effectively protect cells and tissues from oxidative a...

    Authors: Pengxiang Zhao, Zheng Dang, Mengyu Liu, Dazhi Guo, Ruiliu Luo, Mingzi Zhang, Fei Xie, Xujuan Zhang, Youbin Wang, Shuyi Pan and Xuemei Ma
    Citation: Inflammation and Regeneration 2023 43:22
    Content type: Research article Published on:

  9. Since the discovery of group 2 innate lymphoid cells (ILC2s) in 2010, subsequent studies have revealed their developmental pathways, mechanisms of activation and regulation, and immunological roles in tissue h...

    Authors: Maiko Naito and Atsushi Kumanogoh
    Citation: Inflammation and Regeneration 2023 43:21
    Content type: Review Published on:

  10. Alzheimer’s disease (AD) is one of the neurodegenerative diseases and characterized by the appearance and accumulation of amyloid-β (Aβ) aggregates and phosphorylated tau with aging. The aggregation of Aβ, whi...

    Authors: Ryusei Kaneko, Ako Matsui, Mahiro Watanabe, Yoshihiro Harada, Mitsuhiro Kanamori, Natsumi Awata, Mio Kawazoe, Tomoaki Takao, Yutaro Kobayashi, Chie Kikutake, Mikita Suyama, Takashi Saito, Takaomi C. Saido and Minako Ito
    Citation: Inflammation and Regeneration 2023 43:20
    Content type: Research article Published on:

  11. Amyotrophic lateral sclerosis (ALS) is a heterogeneous disease in terms of onset and progression rate. This may account for therapeutic clinical trial failure. Transgenic SOD1G93A mice on C57 or 129Sv backgrou...

    Authors: Cassandra Margotta, Paola Fabbrizio, Marco Ceccanti, Chiara Cambieri, Gabriele Ruffolo, Jessica D’Agostino, Maria Chiara Trolese, Pierangelo Cifelli, Veronica Alfano, Christian Laurini, Silvia Scaricamazza, Alberto Ferri, Gianni Sorarù, Eleonora Palma, Maurizio Inghilleri, Caterina Bendotti…
    Citation: Inflammation and Regeneration 2023 43:19
    Content type: Research article Published on:

    The Correction to this article has been published in Inflammation and Regeneration 2023 43:25

  12. Rheumatoid arthritis (RA) is characterized by chronic inflammation and resultant cartilage/bone destruction because of aberrantly activated osteoclasts. Recently, novel treatments with several Janus kinase (JA...

    Authors: Shinya Yari, Junichi Kikuta, Hotaka Shigyo, Yu Miyamoto, Daisuke Okuzaki, Yuki Furusawa, Masafumi Minoshima, Kazuya Kikuchi and Masaru Ishii
    Citation: Inflammation and Regeneration 2023 43:18
    Content type: Research article Published on:

  13. Extracellular vesicles (EVs) are nano-sized lipid-bilayer encapsulated vesicles produced by the cells. These EVs are released into the surrounding space by almost all cell types. The EVs help in intercellular ...

    Authors: Tasaduq Manzoor, Afnan Saleem, Nida Farooq, Lateef Ahmad Dar, Junaid Nazir, Sahar Saleem, Sameena Ismail, Mudasir Bashir Gugjoo, Parvaiz A. Shiekh and Syed Mudasir Ahmad
    Citation: Inflammation and Regeneration 2023 43:17
    Content type: Review Published on:

  16. The hair follicles (HFs) are barely regenerated after loss in injuries in mammals as well as in human beings. Recent studies have shown that the regenerative ability of HFs is age-related; however, the relatio...

    Authors: Guang Yang, Haiyan Chen, Qun Chen, Jiayi Qiu, Mulan Qahar, Zhimeng Fan, Weiwei Chu, Edward E. Tredget and Yaojiong Wu
    Citation: Inflammation and Regeneration 2023 43:14
    Content type: Research article Published on:

  17. CTLA4Ig is a dimeric fusion protein of the extracellular domain of cytotoxic T-lymphocyte protein 4 (CTLA4) and an Fc (Ig) fragment of human IgG1 that is approved for treating rheumatoid arthritis. However, CTLA4...

    Authors: Fu-Yao Jiang, Yan-Zhu Zhang, Yuan-Hong Tai, Chien-Yu Chou, Yu-Ching Hsieh, Ya-Chi Chang, Hsiao-Chen Huang, Zhi-Qin Li, Yuan-Chin Hsieh, I-Ju Chen, Bo-Cheng Huang, Yu-Cheng Su, Wen-Wei Lin, Hsin-Chieh Lin, Jui-I Chao, Shyng-Shiou F. Yuan…
    Citation: Inflammation and Regeneration 2023 43:13
    Content type: Research article Published on:

  18. Spinal cord injury (SCI) causes nearly all patients to suffer from protracted disabilities. An emerging therapeutic strategy involving the recruitment of endogenous neural stem cells (NSCs) has been developed....

    Authors: Jingyu Wang, Lintao Xu, Deqing Peng, Yongjian Zhu, Zhaowen Gu, Ying Yao, Heyangzi Li, Xi Cao, Chun-yan Fu, Mingzhi Zheng, Xinghui Song, Yueming Ding, Yueliang Shen, Jinjie Zhong, Ying-ying Chen, Jue Hu…
    Citation: Inflammation and Regeneration 2023 43:12
    Content type: Research article Published on:

  19. Canonical Wnt signaling is involved in a variety of biological processes including stem cell renewal and differentiation, embryonic development, and tissue regeneration. Previous studies reported the stage-spe...

    Authors: Takahiro Sogo, Shu Nakao, Tasuku Tsukamoto, Tomoe Ueyama, Yukihiro Harada, Dai Ihara, Tomoaki Ishida, Masato Nakahara, Koji Hasegawa, Yuka Akagi, Yasuyuki S. Kida, Osamu Nakagawa, Teruyuki Nagamune, Masahiro Kawahara and Teruhisa Kawamura
    Citation: Inflammation and Regeneration 2023 43:11
    Content type: Research article Published on:

  20. Inflammation can contribute to the development and progression of cancer. The inflammatory responses in the tumor microenvironment are shaped by complex sequences of dynamic intercellular cross-talks among div...

    Authors: Yoshinobu Konishi and Kenta Terai
    Citation: Inflammation and Regeneration 2023 43:10
    Content type: Review Published on:

  21. To date, many kinds of immune cells have been identified, but their precise roles in intestinal immunity remain unclear. Understanding the in vivo behavior of these immune cells and their function in gastroint...

    Authors: Masaki Honda, Masashi Kadohisa, Daiki Yoshii, Yoshihiro Komohara and Taizo Hibi
    Citation: Inflammation and Regeneration 2023 43:9
    Content type: Review Published on:

  22. Tissue stem cells are confined within a special microenvironment called niche. Stem cells in such a niche are supplied with nutrients and contacted by other cells to maintain their characters and also to keep ...

    Authors: Taichi Kashiwagi, Yuuki Takazawa, Tetsushi Kagawa and Tetsuya Taga
    Citation: Inflammation and Regeneration 2023 43:8
    Content type: Research article Published on:

  23. Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the causative virus of pandemic acute respiratory disease called coronavirus disease 2019 (COVID-19). Most of the infected individuals have asymp...

    Authors: Taisho Yamada and Akinori Takaoka
    Citation: Inflammation and Regeneration 2023 43:7
    Content type: Review Published on:

  25. Wound healing depends largely on the remodeling of the extracellular matrix around and reorganization of tissue-resident cells. Matrix remodeling associated 7 (MXRA7) is a member of the matrix remodeling-assoc...

    Authors: Ying Shen, Jinling Ning, Lu Zhao, Wei Liu, Ting Wang, Jie Yu and Yiqiang Wang
    Citation: Inflammation and Regeneration 2023 43:5
    Content type: Research article Published on:

  26. The coronavirus disease 2019 (COVID-19) pandemic is ongoing because of the repeated emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, highlighting the importance of developing...

    Authors: Ryutaro Kotaki, Saya Moriyama and Yoshimasa Takahashi
    Citation: Inflammation and Regeneration 2023 43:4
    Content type: Review Published on:

  28. Blood coagulation factor XIII (FXIII) promotes cross-linking between fibrin molecules at the final stage of the blood coagulation cascade. However, its expression in cells or tissues and function, particularly...

    Authors: Hirofumi Watanabe, Sho Mokuda, Tadahiro Tokunaga, Hiroki Kohno, Michinori Ishitoku, Kei Araki, Tomohiro Sugimoto, Yusuke Yoshida, Toshihiro Yamamoto, Mayuko Matsumoto, Junya Masumoto, Shintaro Hirata and Eiji Sugiyama
    Citation: Inflammation and Regeneration 2023 43:2
    Content type: Research article Published on:

  33. Subarachnoid hemorrhage (SAH) is a fatal disease, with early brain injury (EBI) occurring within 72 h of SAH injury contributes to its poor prognosis. EBI is a complicated phenomenon involving multiple mechani...

    Authors: Hiroki Yamada, Yoshitaka Kase, Yuji Okano, Doyoon Kim, Maraku Goto, Satoshi Takahashi, Hideyuki Okano and Masahiro Toda
    Citation: Inflammation and Regeneration 2022 42:61
    Content type: Research article Published on:

  34. To understand disease pathophysiologies, models that recapitulate human functions are necessary. In vitro models that consist of human cells are preferred to ones using animal cells, because organ functions ca...

    Authors: Sayaka Deguchi and Kazuo Takayama
    Citation: Inflammation and Regeneration 2022 42:62
    Content type: Review Published on:

  37. The high transmissibility and rapid global spread of SARS-CoV-2 since 2019 has led to a huge burden on healthcare worldwide. Anti-SARS-CoV-2 neutralizing antibodies play an important role in not only protectin...

    Authors: Yafei Liu and Hisashi Arase
    Citation: Inflammation and Regeneration 2022 42:58
    Content type: Review Published on:

  40. The molecular platforms of the innate immune system are essential to recognize pathologic external factors that are crucial to differentiate these danger signals from host motifs. A set of sensors recognizing ...

    Authors: Atsushi Kawakami, Yushiro Endo, Tomohiro Koga, Koh-ichiro Yoshiura and Kiyoshi Migita
    Citation: Inflammation and Regeneration 2022 42:37
    Content type: Review Published on:

    The Correction to this article has been published in Inflammation and Regeneration 2022 42:64

  41. Brachial plexus avulsion (BPA) physically involves the detachment of spinal nerve roots themselves and the associated spinal cord segment, leading to permanent paralysis of motor function of the upper limb. Ro...

    Authors: Yanfeng Huang, Xie Zhang, Qionghui Huang, Yaoxing Dou, Chang Qu, Qingqing Xu, Qiuju Yuan, Yan-Fang Xian and Zhi-Xiu Lin
    Citation: Inflammation and Regeneration 2022 42:56
    Content type: Research article Published on:

  42. Recent advances in our understanding in the immune-mediated inflammatory diseases (IMID) are explored and promoted by the targeted treatment. Among these targets, cytokines and cytokine receptors have become t...

    Authors: Tsutomu Takeuchi
    Citation: Inflammation and Regeneration 2022 42:35
    Content type: Review Published on:

    The Correction to this article has been published in Inflammation and Regeneration 2022 42:63

  43. Type 1 diabetes (T1D) is a T-cell-mediated autoimmune disease characterized by the irreversible destruction of insulin-producing β-cells in pancreatic islets. Helper and cytotoxic T-cells and cytokine producti...

    Authors: Basak Isildar, Serbay Ozkan, Merve Ercin, Selda Gezginci-Oktayoglu, Mahmut Oncul and Meral Koyuturk
    Citation: Inflammation and Regeneration 2022 42:55
    Content type: Research article Published on:

  45. The coronavirus disease 2019 (COVID-19) pandemic is widespread; however, accurate predictors of refractory cases have not yet been established. Circulating extracellular vesicles, involved in many pathological...

    Authors: Takahiro Kawasaki, Yoshito Takeda, Ryuya Edahiro, Yuya Shirai, Mari Nogami-Itoh, Takanori Matsuki, Hiroshi Kida, Takatoshi Enomoto, Reina Hara, Yoshimi Noda, Yuichi Adachi, Takayuki Niitsu, Saori Amiya, Yuta Yamaguchi, Teruaki Murakami, Yasuhiro Kato…
    Citation: Inflammation and Regeneration 2022 42:53
    Content type: Research article Published on:

  46. Different factors may lead to hepatitis. Among which are liver inflammation and poisoning. We chose two hepatitis models, typical for these two underlying causes. Thus, we aimed to characterize the role of pro...

    Authors: Gal Reches, Netta R. Blondheim Shraga, Florent Carrette, Assaf Malka, Natalia Saleev, Yehuda Gubbay, Offir Ertracht, Izhak Haviv, Linda M. Bradley, Fred Levine and Ron Piran
    Citation: Inflammation and Regeneration 2022 42:52
    Content type: Research article Published on:

  47. As an important part of adaptive immunity, T cells are indispensable in the defense against pathogens including viruses. SARS-CoV-2 is a new human coronavirus that occurred at the end of 2019 and has caused th...

    Authors: Xiuyuan Lu and Sho Yamasaki
    Citation: Inflammation and Regeneration 2022 42:51
    Content type: Review Published on:

  48. Coronaviruses regularly cause outbreaks of zoonotic diseases characterized by severe pneumonia. The new coronavirus, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused the global pandemic...

    Authors: Shin-ichiro Fujii, Satoru Yamasaki, Tomonori Iyoda and Kanako Shimizu
    Citation: Inflammation and Regeneration 2022 42:50
    Content type: Review Published on:

  49. The emerging concepts of fetal-like reprogramming following tissue injury have been well recognized as an important cue for resolving regenerative mechanisms of intestinal epithelium during inflammation. We pr...

    Authors: Sakurako Kobayashi, Nobuhiko Ogasawara, Satoshi Watanabe, Yosuke Yoneyama, Sakura Kirino, Yui Hiraguri, Masami Inoue, Sayaka Nagata, Yoshimi Okamoto-Uchida, Satoshi Kofuji, Hiromichi Shimizu, Go Ito, Tomohiro Mizutani, Shinichi Yamauchi, Yusuke Kinugasa, Yoshihito Kano…
    Citation: Inflammation and Regeneration 2022 42:49
    Content type: Research article Published on:


The official journal of the Japanese Society of Inflammation and Regeneration.

Submit manuscript

Follow

Annual Journal Metrics

Inflammation and Regeneration

ISSN: 1880-8190

Contact us